Synolis VA is a smart gel that is injected into the joint(s) affected by osteoarthritis (OA). With Synolis VA, you can expect fast and intense relief from pain, as well as improved joint function. Synolis VA works across all types of osteoarthritis. It can be given by your doctor to treat mild, moderate and severe osteoarthritis. Synolis VA is made up of a unique combination of hyaluronic acid (HA) and sorbitol.